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The 6th JCA-AACR Special Joint Conference

PDF Meet the Expert Evening (101KB)

The Latest Advances in Lung Cancer Research:
From Basic Science to Therapeutics

July 10 (Tue)-12 (Thu), 2018

Gojo-sagaru, Horikawa-dori, Shimogyo-ku,
Kyoto-shi, Kyoto 600-8519, Japan
TEL: +81-75-341-2411
https://www.tokyuhotelsjapan.com/en/hotel/
TH/TH_KYOTO/index.html


                   
Abstract Submission Deadline:
April 30, 2018 May 13, 2018

Registration Deadline: June 8, 2018


 (Required)


Organizing Committee:
JCA   Hiroyuki Mano (National Cancer Center)
       Seiji Yano (Kanazawa University)
       Hiroyoshi Nishikawa (National Cancer Center)

AACR  Alice T. Shaw (Massachusetts General Hospital Cancer Center)
       Roy S. Herbst (Yale Cancer Center)
       Charles M. Rudin (Memorial Sloan Kettering Cancer Center)

Program (tentative)


July 10
Time Session Chairperson Speaker Title
18:00-18:10 Welcome Address
18:10-19:30 Keynote Alice T. Shaw

Hiroyuki Mano
Hiroyuki Mano
(National Cancer Center Research Institute)
Construction of Cancer Genomic Medicine Platform in Japan
Alice T. Shaw
(Massachusetts General Hospital)
Evolution of Resistance and Tumor Heterogeneity in ALK-Positive Lung Cancer
19:50-21:50 Welcome Party
July 11
Time Session Chairperson Speaker Title
8:30-10:00 1. Personalized treatment strategies in lung cancer Alexander E. Drilon

Koichi Goto
Shinji Kohsaka
(National Cancer Center Research Institute)
Application of a High-throughput Functional Evaluation of Variants of Unknown Significance to Personalized Medicine
Alexander E. Drilon
(Memorial Sloan Kettering Cancer Center)
Advances in Targeted Therapy For Driver-Positive Subsets Of Non-Small Cell Lung Cancers
Koichi Goto
(National Cancer Center Hospital East)
Development of a Nationwide Genomic Screening Project (LC-SCRUM-Japan) for the Establishment of Precision Medicine in Lung Cancer
10:00-10:20 Break
10:20-11:50 2. Latest advances in small cell lung cancer and mesothelioma Charles M. Rudin

Hiroyuki Aburatani
Charles M. Rudin
(Memorial Sloan Kettering Cancer Center)
Latest Advances in Small Cell Lung Cancer
Hiroyuki Aburatani
(The University of Tokyo)
Comprehensive Molecular Analysis of Malignant Pleural Mesothelioma
Shoutaro Tsuji
(Kanagawa Cancer Center)
Development of Precise Diagnosis with a New Mesothelioma Marker, Sialylated HEG1
11:50-12:50 Lunch and Poster View
12:50-14:20 Poster Presentation
14:20-15:50 3. Targeting KRAS-mutant lung cancer Ferdinandos Skoulidis

Hiroki Nagase
Ferdinandos Skoulidis
(The University of Texas MD Anderson Cancer Center)
Dissecting Immunotherapy Responses in Subgroups of KRAS-Mutant Lung Adenocarcinoma
Hiromichi Ebi
(Aichi Cancer Center)
Combination Therapies Targeting KRAS Mutant Lung Cancer
Hiroki Nagase
(Chiba Cancer Center Research Institute)
Targeting the RAS Gene Against Cancer
15:50-16:10 Break
16:10-17:40 4. Overcoming resistance to targeted therapies in lung cancer Christine M. Lovly

Takashi Takahashi
Takashi Takahashi
(Nagoya University Graduate School of Medicine)
ROR1: An Achilles Heel of Lung Cancer
Christine M. Lovly
(Vanderbilt University Medical Center)
Overcoming Resistance to Mutant-Selective EGFR Inhibition in EGFR-mutant Lung Cancer
Ryohei Katayama
(Cancer Chemotherapy Center of JFCR)
Drug Repurposing: Overcoming the Acquired Resistance with Other Target Inhibitors
18:00-19:00 Meet-the-Expert Evening (all participants)
19:30-21:30 Banquet
July 12
Time Session Chairperson Speaker Title
8:30-10:00 5. Novel immunotherapy strategies: Beyond PD-1/PD-L1 Justin F. Gainor

Hiroyoshi Nishikawa
Hiroyoshi Nishikawa
(National Cancer Center Research Institute)
Complexed Immune Suppressive Michanisms In Tumor Microenvironment
Justin F. Gainor
(Massachusetts General Hospital)
Emerging Immunotherapy Combinations in the Management of Non-Small Cell Lung Cancer
Koji Tamada
(Yamaguchi University Graduate School of Medicine)
Revolution of CAR-T Cell Technology to Develop Next-generation Cancer Immunotherapy
10:00-10:20 Break
10:20-11:50 6. Primary and acquired mechanisms of resistance to immunotherapies Roy S. Herbst

Heiichiro Udono
Kenji Chamoto
(Kyoto University)
The Role of Fatty Acid Oxidation of T Cells in the Synergistic Effect With PD-1 Blockade
Heiichiro Udono
(Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences)
Anti-diabetes Drug, Metformin, Drives Metabolic Reprogramming of Tumor Microenvironment, Leading to Inhibition of Tumor Growth
Roy S. Herbst
(Yale Cancer Center)
Primary and Acquired Mechanisms of Resistance to Immunotherapies
11:50-12:50 Lunch
12:50-14:20 7. Tumor heterogeneity and circulating tumor DNA Maximilian Diehn

Seiji Yano
Seiji Yano
(Cancer Research Institute of Kanazawa University)
Inter-organ Heterogeneity on Mechanisms of Targeted Drug Resistance -Central Nervous System (CNS) vs extra CNS-
Maximilian Diehn
(Stanford University)
Circulating Tumor DNA Analysis for Personalized Cancer Detection and Monitoring
Tsukasa Kadota
(National Cancer Center Research Institute)
Circulating MicroRNAs as Biomarkers for Early Detection and Prediction of Immunotherapeutic Response in Lung Cancer Patients
14:20-14:40 Break
14:40-16:10 8. Tumor microenvironment and implications for treatment Miguel F. Sanmamed

Kohei Miyazono
Atsushi Enomoto
(Nagoya University Graduate School of Medicine)
Heterogeneity of Cancer-Associated Fibroblasts and its Significance in Tumor Progression and Response to Therapies
Miguel F. Sanmamed
(Yale University)
Modeling Patient-derived Lung Tumor Microenvironment To Develop Immunotherapies
Kohei Miyazono
(The University of Tokyo)
Regulation of the Development of Lung Cancer by TGF-β Signaling
16:10-16:20 Closing Remarks

Travel Grant

  1. The Japanese Cancer Association (JCA) and the Organizing Committee of the 6th JCA-AACR Special Joint Conference will be offering travel grants to up to 5 to 7 foreign abstract registrants who will be presenting at the 6th JCA-AACR Special Joint Conference. This grant is intended to defray the cost of attending the conference and will be offered to participants whose abstracts have been accepted for presentation.

    * The applicant must be the first author of the submitted abstract and must present the paper at the 6th JCA-AACR Special Joint Conference.

    * The applicant must be a researcher who is of non-Japanese nationality

    * The Organizing Committee members will review all the submitted abstracts and application forms and select the grant recipients.

  2. We will award JPY100,000 per person.

  3. The application deadline is April 30, 2018 May 13, 2018
Please upload your abstract and the travel grant application form to the abstract submission site. We will notify all applicants of the result prior to the conference. Please download the application form from here.