ミーティング

The 5th JCA-AACR Special Joint Conference

PDF Instructions for Oral presenters(133KB)

PDF Instructions for Poster presenters(34KB)

PDF Meet the Expert Evening (tentative)(80KB)

The Latest Advances in Hematological Cancer Research:
From Basic Science to Therapeutics

July 13-15, 2016

Tokyo Bay Maihama Hotel Club Resort
1-7, Maihama, Urayasu-shi, Chiba 279-0031, Japan
TEL: +81-47-355-2411
http://www.tbm-clubresort.jp/eng/


                     April 29, 2016
Abstract Submission Deadline: April 15, 2016
*We have extended the deadline
for abstract submission.


Registration Deadline: June 17, 2016


※We closed the abstract submission

 (Required)


Organizing Committee:
JCA   Dr.Takuro Nakamura (The Cancer Institute of JFCR)
      Dr.Issay Kitabayashi (National Cancer Center)
      Dr.Shigeru Chiba (University of Tsukuba)

AACR  Dr.Jonathan D. Licht (University of Florida Health Cancer Center)
      Dr.Ross L. Levine (Memorial Sloan Kettering Cancer Center)
      Dr.Catriona Jamieson (Moores UC San Diego Cancer Center)

Program (tentative)

July 13
Time Session Chairperson Speaker Title
18:00-18:10 Welcome Address
18:10-19:30 Keynote Dr.Licht
Dr.Nakamura
Dr. Jonathan D. Licht
(The University of Florida)
Disordered Histone Methylation in Lymphoid Malignancy
Dr.Takuro Nakamura
(The Cancer Institute of JFCR)
Signaling and Transcriptional Networks in Myeloid Leukemogenesis
20:00-22:00 Welcome Party
July 14
Time Session Chairperson Speaker Title
8:00-9:30 1. Aging and epigenetics in hematopoietic malignancies Dr.Figueora
Dr.Chiba
Dr.Atsushi Iwama
(Chiba University)
Deregulated polycomb-group gene functions in hematological malignancies
Dr.Maria E. (Ken) Figueroa
(University of Michigan)
Epigenetic deregulation in the aging hematopoietic stem cell
Dr.Shigeru Chiba
(University of Tsukuba)
Aging and TET Dioxygenases in Leukemo/lymphomagenesis
9:30-9:50 Break
9:50-11:20 2. Myeloproliferative neoplasms and myelodysplastic syndrome Dr.Levine
Dr.Kitamura
Dr.Ross L. Levine (Memorial Sloan Kettering Cancer Center) Role of JAK-STAT Pathway Activation in MPN Pathogenesis And Therapeutic Response
Dr.Toshio Kitamura (The University of Tokyo) The ASXL1 mutation and the EZH2 mutation induced myelodysplastic syndromes in mice via distinct mechanisms
Dr.Hitoshi Takizawa (Kumamoto University) Inflammation-induced Malignant Transformation of Hematopoietic Stem Cell
11:20-12:20 Lunch and Poster View
12:20-13:50 Poster Presentation
13:50-15:20 3. Recent advances in lymphoma therapeutics Dr.Melnick Dr.Tobinai Dr.Ari Melnick
(Weill Cornell Medicine)
Epigenetic circuits and their perturbation in lymphoid neoplasms
Dr.Kensei Tobinai (National Cancer Center Hospital) New agent development for lymphoid malignancies in Japan
Dr.Yasuhito Terui (Cancer Institute Hospital of JFCR) Recent advances in therapeutics for B-cell lymphoma
15:20-15:40 Break
15:40-17:40 4. Leukemogenesis: Leukemia stem cell, metabolism and novel targets Dr.Jamieson Dr.Kitabayashi Dr.Atsushi Hirao (Kanazawa University) Molecular mechanism linking stem cell aging and tumorigenesis in hematopoiesis
Dr.Catriona H. M. Jamieson
(UC San Diego)
Malignant RNA Editing Activation Drives Cancer Stem Cell Self-renewal by Impairing Let-7 Biogenesis
Dr.Koicji Akashi (Kyushu University) Malignant RNA Editing Activation Drives Cancer Stem Cell Self-renewal by Impairing Let-7 Biogenesis
Dr.Issay Kitabayashi (National Cancer Center Research Institute) Novel leukemia stem cell-targeted therapy for acute myeloid leukemia based on dual inhibition of EZH1/EZH2
18:00-19:00 Meet the Expert (all participants)
19:30-21:30 Banquet
July 15
Time Session Chairperson Speaker Title
8:30-10:00 5. Genetic and epigenetic alterations in childhood leukemia Dr.Ferrando Dr.Ito Dr.Junko Takita (The Univeristy of Tokyo) Integrated Genetic Analysis of Pediatric T-cell Acute Lymphoblastic Leukemia
Dr.Adolfo A. Ferrando (Columbia University) Oncogenic signaling pathways and mechanisms of resistance in acute lymphoblastic leukemia
Dr.Etsuro Ito (Hirosaki University) Genetic and Epigenetic Alterations in Acute Megakaryoblastic Leukemia in Down Syndrome
10:00-10:20 Break
10:20-11:50 6. Genomic landscapes of lymphoid malignancies Dr.Landau Dr.Mano Dr.Seishi Ogawa (Kyoto University) A novel genetic mechanism of evading anti-tumor immunity in multiple human cancers
Dr.Dan A. Landau (Weill Cornell Medicine) Genetic and epigenetic determinants of chronic lymphocytic leukemia evolution
Dr.Hiroyuki Mano (The University of Tokyo) Discovery of DUX4-IGH Fusion-Type Oncogene In B-Cell Acute Lymphoblastic Leukemia Of AYA Generation
11:50-12:50 Lunch and Poster View
12:50-14:20 7. Immunotherapy of hematopoietic neoplasms Dr.Riddell
Dr.Kawakami
Dr.Yutaka Kawakami
(Keio University)
Personalized Combinatorial Modulation of Tumor Microenvironments for Effective Cancer Immunotherapy
Dr.Hiroyoshi Nishikawa (National Cancer Center) Critical Role of Regulatory T cells in Cancer Immunotherapy For Hematologic Malignancies
Dr.Stanley R. Riddell(Fred Hutchinson Cancer Research Center) Engineering Safe and Effective T Cell Therapy For Cancer
14:20-14:40 Break
14:40-15:40 8. Molecular biology and targets of multiple myeloma Dr.Tiedemann Dr.Furukawa Dr.Rodger E. Tiedemann (University of Toronto) Intra-Tumor Heterogeneity In Multiple Myeloma And It’s Role In Therapeutic Resistance And Relapse
Dr.Yusuke Furukawa
(Jichi Medical University)
Epigenetic mechanisms of drug resistance in multiple myeloma
15:40-15:50 Closing Remarks